41 research outputs found

    Assessment of Electrical Safety Beliefs and Practices: A Case Study

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    In this paper, the electrical safety beliefs and practices in Hail region, Saudi Arabia, have been assessed. Based on legislative recommendations and rules applied in Saudi Arabia, on official statistics regarding the electricity-caused accidents and on the analysis of more than 200 photos captured in Hail (related to electrical safety), a questionnaire composed of 36 questions (10 for the respondents information, 16 for the home safety culture and 10 for the electrical devices purchasing culture) has been devised and distributed to residents. 228 responses have been collected and analyzed. Using a scale similar to the one adopted for a university student GPA calculation, the electrical safety level (ESL) in Hail region has been found to be 0.76 (in a scale of 4 points) which is a very low score and indicates a poor electrical safety culture. Several recommendations involving different competent authorities have been proposed. Future work will concern the assessment of safety in industrial companies in Hail region

    L\'amylose Laryngée À Propos D\'un Cas

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    L\'amylose localisée est caractérisée par un dépôt de protéines fibrillaires dans un site de l\'organisme sans atteinte systémique. La localisation laryngée est très rare. Ce diagnostic doit être évoqué devant toute lésion d\'allure bénigne du larynx. Les auteurs rapportent un cas d\'amylose laryngée colligé sur une période de 10 ans.Localized amyloidosis is characterized by the deposition of amyloid fibres in a particular site or organ system in the absence of systemic involvement. The laryngeal location of amylosis is rare. The diagnosis must be suspected in front of any tumor of benign speed of the larynx. Authors report a case of laryngeal amyloidosis brought during a period of 10 years. Journal Tunisien d\'ORL et de chirurgie cervico-faciale Vol. 16 2006: pp. 30-3

    Le Carcinome Mucoépidermoïde De La Parotide : Apropos De 5 Cas

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    Les tumeurs des glandes salivaires représentent moins de 5% de toutes les tumeurs de la tête et du cou. Parmi eux, le carcinome mucoépidermoïde est la tumeur la plus fréquente. Quarante cinq pour cent des carcinomes mucoépidermoïdes se développent au niveau de la glande parotide. Cette lésion se voit surtout chez l\'adulte vers la 5ème décade. Le diagnostic est confirmé seulement à l\'examen anatomopathologique. Son pronostic est fonction des critères histologiques.Salivary gland tumors account for less than 5% of the head and neck neoplasms. Among them, mucoepidermoid carcinoma is the most common malignant salivary gland tumor. About 45% of mucoepidermoid carcinomas occur in the parotid gland, and appear around the fifth decade of life. A certain diagnostic can be obtained only after post-operative histological examination. Histological examination indicates the patient prognosis. Journal Tunisien d\'ORL et de chirurgie cervico-faciale Vol. 16 2006: pp. 39-4

    A community effort in SARS-CoV-2 drug discovery.

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    peer reviewedThe COVID-19 pandemic continues to pose a substantial threat to human lives and is likely to do so for years to come. Despite the availability of vaccines, searching for efficient small-molecule drugs that are widely available, including in low- and middle-income countries, is an ongoing challenge. In this work, we report the results of an open science community effort, the "Billion molecules against Covid-19 challenge", to identify small-molecule inhibitors against SARS-CoV-2 or relevant human receptors. Participating teams used a wide variety of computational methods to screen a minimum of 1 billion virtual molecules against 6 protein targets. Overall, 31 teams participated, and they suggested a total of 639,024 molecules, which were subsequently ranked to find 'consensus compounds'. The organizing team coordinated with various contract research organizations (CROs) and collaborating institutions to synthesize and test 878 compounds for biological activity against proteases (Nsp5, Nsp3, TMPRSS2), nucleocapsid N, RdRP (only the Nsp12 domain), and (alpha) spike protein S. Overall, 27 compounds with weak inhibition/binding were experimentally identified by binding-, cleavage-, and/or viral suppression assays and are presented here. Open science approaches such as the one presented here contribute to the knowledge base of future drug discovery efforts in finding better SARS-CoV-2 treatments.R-AGR-3826 - COVID19-14715687-CovScreen (01/06/2020 - 31/01/2021) - GLAAB Enric

    Combatting mucosal melanoma: recent advances and future perspectives

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